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Identification of Novel HIV 1- Protease Inhibitors: Application of Ligand and Structure Based Pharmacophore Mapping and Virtual Screening
A combined ligand and structure-based drug design approach provides a synergistic advantage over either methods performed individually. Present work bestows a good assembly of ligand and structure-based pharmacophore generation concept. Ligand-oriented study was accomplished by employing the HypoGen...
Autores principales: | Yadav, Divya, Paliwal, Sarvesh, Yadav, Rakesh, Pal, Mahima, Pandey, Anubhuti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493599/ https://www.ncbi.nlm.nih.gov/pubmed/23145032 http://dx.doi.org/10.1371/journal.pone.0048942 |
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