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Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma

BACKGROUND: Therapeutic vaccination directed to induce an anti-tumoral T-cell response is a field of extensive investigation in the treatment of melanoma. However, many vaccination trials in melanoma failed to demonstrate a correlation between the vaccine-specific immune response and therapy outcome...

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Detalles Bibliográficos
Autores principales: Becker, Jürgen C., Andersen, Mads H., Hofmeister-Müller, Valeska, Wobser, Marion, Frey, Lidia, Sandig, Christiane, Walter, Steffen, Singh-Jasuja, Harpreet, Kämpgen, Eckhart, Opitz, Andreas, Zapatka, Marc, Bröcker, Eva-B., thor Straten, Per, Schrama, David, Ugurel, Selma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493663/
https://www.ncbi.nlm.nih.gov/pubmed/22565484
http://dx.doi.org/10.1007/s00262-012-1266-9