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Construction of PR39 recombinant AAV under control of the HRE promoter and the effect of recombinant AAV on gene therapy of ischemic heart disease

The objective of this study was to investigate the effect of the PR39 recombinant adeno-associated virus (AAV) controlled by the hypoxia-responsive element (HRE) on gene therapy of ischemic heart disease. The minimal HRE was artificially synthesized and the AAV vector controlled by HRE was introduce...

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Detalles Bibliográficos
Autores principales: SUN, LIJUN, HAO, YUEWEN, NIE, XIAOWEI, ZHANG, XUEXIN, YANG, GUANGXIAO, WANG, QUANYING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493712/
https://www.ncbi.nlm.nih.gov/pubmed/23226731
http://dx.doi.org/10.3892/etm.2012.674