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Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma

The catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), is highly active in immortalized cells and more than 90% of human cancer cells, but is quiescent in the majority of normal somatic cells. Thus, the hTERT promoter has been extensively used in targeted cancer gene th...

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Detalles Bibliográficos
Autores principales: ZHANG, PING, TAN, JIAO, YANG, DA-BING, LUO, ZI-CHAO, LUO, SHAN, CHEN, PING, SUN, PING, ZHOU, YI, CHEN, XIAN-CHENG, WEI, YU-QUAN, WEN, YAN-JUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493746/
https://www.ncbi.nlm.nih.gov/pubmed/23226739
http://dx.doi.org/10.3892/etm.2012.679