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Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma
The catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), is highly active in immortalized cells and more than 90% of human cancer cells, but is quiescent in the majority of normal somatic cells. Thus, the hTERT promoter has been extensively used in targeted cancer gene th...
Autores principales: | ZHANG, PING, TAN, JIAO, YANG, DA-BING, LUO, ZI-CHAO, LUO, SHAN, CHEN, PING, SUN, PING, ZHOU, YI, CHEN, XIAN-CHENG, WEI, YU-QUAN, WEN, YAN-JUN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493746/ https://www.ncbi.nlm.nih.gov/pubmed/23226739 http://dx.doi.org/10.3892/etm.2012.679 |
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