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The TLR5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens

Allergic asthma is a complex disease characterized by eosinophilic pulmonary inflammation, mucus production and reversible airway obstruction(1). Exposure to indoor allergens is a clear risk factor for asthma, but this disease is also associated with high household levels of total and Gram-negative...

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Detalles Bibliográficos
Autores principales: Wilson, Rhonda H., Maruoka, Shuichiro, Whitehead, Gregory S., Foley, Julie F., Flake, Gordon P., Sever, Michelle L., Zeldin, Darryl C., Kraft, Monica, Garantziotis, Stavros, Nakano, Hideki, Cook, Donald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493750/
https://www.ncbi.nlm.nih.gov/pubmed/23064463
http://dx.doi.org/10.1038/nm.2920