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The TLR5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens
Allergic asthma is a complex disease characterized by eosinophilic pulmonary inflammation, mucus production and reversible airway obstruction(1). Exposure to indoor allergens is a clear risk factor for asthma, but this disease is also associated with high household levels of total and Gram-negative...
Autores principales: | Wilson, Rhonda H., Maruoka, Shuichiro, Whitehead, Gregory S., Foley, Julie F., Flake, Gordon P., Sever, Michelle L., Zeldin, Darryl C., Kraft, Monica, Garantziotis, Stavros, Nakano, Hideki, Cook, Donald N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493750/ https://www.ncbi.nlm.nih.gov/pubmed/23064463 http://dx.doi.org/10.1038/nm.2920 |
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