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Ligand-independent activation of EphA2 by arachidonic acid induces metastasis-like behaviour in prostate cancer cells
BACKGROUND: High intake of omega-6 polyunsaturated fatty acids (PUFA) has been associated with clinical progression in prostate cancer (CaP). This study investigates the signalling mechanism by which the omega-6 PUFA arachidonic acid (AA) induces prostatic cellular migration to bone marrow stroma. M...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493871/ https://www.ncbi.nlm.nih.gov/pubmed/23037715 http://dx.doi.org/10.1038/bjc.2012.457 |