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Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway

BACKGROUND: Targeting differentially activated or perturbed tumour pathways is the key idea in individualised cancer therapy, which is emerging as an important option in treating cancers with poor prognostic profiles. TP53 mutation status is known as a core determinant of survival in breast cancer....

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Detalles Bibliográficos
Autores principales: Joshi, H, Bhanot, G, Børresen-Dale, A-L, Kristensen, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493873/
https://www.ncbi.nlm.nih.gov/pubmed/23079576
http://dx.doi.org/10.1038/bjc.2012.461