Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

Drug resistance continues to be a major barrier to the delivery of curative therapies in cancer. Historically, drug resistance has been associated with over-expression of drug transporters, changes in drug kinetics or amplification of drug targets. However, the emergence of resistance in patients tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Saunders, Nicholas A, Simpson, Fiona, Thompson, Erik W, Hill, Michelle M, Endo-Munoz, Liliana, Leggatt, Graham, Minchin, Rodney F, Guminski, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494067/
https://www.ncbi.nlm.nih.gov/pubmed/22733553
http://dx.doi.org/10.1002/emmm.201101131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494067/
https://www.ncbi.nlm.nih.gov/pubmed/22733553
http://dx.doi.org/10.1002/emmm.201101131

Ejemplares similares