Cargando…
Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives
Drug resistance continues to be a major barrier to the delivery of curative therapies in cancer. Historically, drug resistance has been associated with over-expression of drug transporters, changes in drug kinetics or amplification of drug targets. However, the emergence of resistance in patients tr...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
WILEY-VCH Verlag
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494067/ https://www.ncbi.nlm.nih.gov/pubmed/22733553 http://dx.doi.org/10.1002/emmm.201101131 |