Deleterious effects of neuronal accumulation of glycogen in flies and mice

Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora disease or other polyglucosan disorders. Although these...

Descripción completa

Detalles Bibliográficos
Autores principales: Duran, Jordi, Tevy, María Florencia, Garcia-Rocha, Mar, Calbó, Joaquim, Milán, Marco, Guinovart, Joan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494072/
https://www.ncbi.nlm.nih.gov/pubmed/22549942
http://dx.doi.org/10.1002/emmm.201200241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494072/
https://www.ncbi.nlm.nih.gov/pubmed/22549942
http://dx.doi.org/10.1002/emmm.201200241

Ejemplares similares