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Deleterious effects of neuronal accumulation of glycogen in flies and mice
Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora disease or other polyglucosan disorders. Although these...
Autores principales: | Duran, Jordi, Tevy, María Florencia, Garcia-Rocha, Mar, Calbó, Joaquim, Milán, Marco, Guinovart, Joan J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494072/ https://www.ncbi.nlm.nih.gov/pubmed/22549942 http://dx.doi.org/10.1002/emmm.201200241 |
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