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Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines

Stromal–epithelial interaction is crucial to mediate normal prostate and prostate cancer (PCa) development. The indispensable roles of mesenchymal/stromal androgen receptor (AR) for the prostate organogenesis have been demonstrated by using tissue recombination from wild-type and testicular feminize...

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Detalles Bibliográficos
Autores principales: Lai, Kuo-Pao, Yamashita, Shinichi, Huang, Chiung-Kuei, Yeh, Shuyuan, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494077/
https://www.ncbi.nlm.nih.gov/pubmed/22745041
http://dx.doi.org/10.1002/emmm.201101140