p53 suppresses type II endometrial carcinomas in mice and governs endometrial tumour aggressiveness in humans

Type II endometrial carcinomas are a highly aggressive group of tumour subtypes that are frequently associated with inactivation of the TP53 tumour suppressor gene. We show that mice with endometrium-specific deletion of Trp53 initially exhibited histological changes that are identical to known prec...

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Detalles Bibliográficos
Autores principales: Wild, Peter J, Ikenberg, Kristian, Fuchs, Thomas J, Rechsteiner, Markus, Georgiev, Strahil, Fankhauser, Niklaus, Noske, Aurelia, Roessle, Matthias, Caduff, Rosmarie, Dellas, Athanassios, Fink, Daniel, Moch, Holger, Krek, Wilhelm, Frew, Ian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494078/
https://www.ncbi.nlm.nih.gov/pubmed/22678923
http://dx.doi.org/10.1002/emmm.201101063

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