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PLK1 gene suppresses cell invasion of undifferentiated thyroid carcinoma through the inhibition of CD44v6, MMP-2 and MMP-9

The aim of this study was to observe the regulatory action of the polo-like kinase 1 (PLK1) gene in the invasion of anaplastic thyroid carcinoma cells and investigate its mechanisms. The expression of the PLK1 protein in 36 patients with anaplastic thyroid carcinoma was detected by immunohistochemic...

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Detalles Bibliográficos
Autores principales: ZHANG, XING-GUANG, LU, XIAO-FENG, JIAO, XIU-MING, CHEN, BIN, WU, JIN-XIAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494126/
https://www.ncbi.nlm.nih.gov/pubmed/23226764
http://dx.doi.org/10.3892/etm.2012.729