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Low prevalence of transmitted K65R and other tenofovir resistance mutations across different HIV-1 subtypes: implications for pre-exposure prophylaxis

INTRODUCTION: Tenofovir-containing regimens have demonstrated potential efficacy as pre-exposure prophylaxis (PrEP) in preventing HIV-1 infection. Transmitted drug resistance mutations associated with tenofovir, specifically the reverse transcriptase (RT) mutation K65R, may impact the effectiveness...

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Detalles Bibliográficos
Autores principales: Chan, Philip A, Huang, Austin, Kantor, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494163/
https://www.ncbi.nlm.nih.gov/pubmed/23305651
http://dx.doi.org/10.7448/IAS.15.2.17701