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A Method for Large-scale Identification of Protein Arginine Methylation

The lack of methods for proteome-scale detection of arginine methylation restricts our knowledge of its relevance in physiological and pathological processes. Here we show that most tryptic peptides containing methylated arginine(s) are highly basic and hydrophilic. Consequently, they could be consi...

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Detalles Bibliográficos
Autores principales: Uhlmann, Thomas, Geoghegan, Vincent L., Thomas, Benjamin, Ridlova, Gabriela, Trudgian, David C., Acuto, Oreste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494207/
https://www.ncbi.nlm.nih.gov/pubmed/22865923
http://dx.doi.org/10.1074/mcp.M112.020743