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Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization

Mitochondrial dysfunction has been implicated in the pathogenesis of type 2 diabetes. Identifying novel regulators of mitochondrial bioenergetics will broaden our understanding of regulatory checkpoints that coordinate complex metabolic pathways. We previously showed that Nur77, an orphan nuclear re...

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Detalles Bibliográficos
Autores principales: Chao, Lily C., Wroblewski, Kevin, Ilkayeva, Olga R., Stevens, Robert D., Bain, James, Meyer, Gretchen A., Schenk, Simon, Martinez, Leonel, Vergnes, Laurent, Narkar, Vihang A., Drew, Brian G., Hong, Cynthia, Boyadjian, Rima, Hevener, Andrea L., Evans, Ronald M., Reue, Karen, Spencer, Melissa J., Newgard, Christopher B., Tontonoz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494265/
https://www.ncbi.nlm.nih.gov/pubmed/23028113
http://dx.doi.org/10.1194/jlr.M029355