Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1

Thrombospondin-1 is a matricellular protein with potent antitumour activities, the levels of which determine the fate of many different tumours, including renal carcinomas. However, the factors that regulate this protein remain unclear. In renal carcinomas, hypoxic conditions enhance the expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Bienes-Martínez, Raquel, Ordóñez, Angel, Feijoo-Cuaresma, Mónica, Corral-Escariz, María, Mateo, Gloria, Stenina, Olga, Jiménez, Benilde, Calzada, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494377/
https://www.ncbi.nlm.nih.gov/pubmed/23145312
http://dx.doi.org/10.1038/srep00788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494377/
https://www.ncbi.nlm.nih.gov/pubmed/23145312
http://dx.doi.org/10.1038/srep00788

Ejemplares similares