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miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence

BACKGROUND: Radio- and chemotherapy (RT/CT) resistance hampers success in combating small and non-small cell lung cancers (SCLC/NSCLC). The underlying molecular mechanisms of RT/CT resistance of LCs are multifactorial and have been understood in part hitherto. miRNAs, key regulators of mRNAs, are we...

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Detalles Bibliográficos
Autores principales: Salim, H, Akbar, N S, Zong, D, Vaculova, A H, Lewensohn, R, Moshfegh, A, Viktorsson, K, Zhivotovsky, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494421/
https://www.ncbi.nlm.nih.gov/pubmed/22929890
http://dx.doi.org/10.1038/bjc.2012.382