Notch-mediated induction of N-cadherin and α9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells

BACKGROUND: Rhabdomyosarcoma (RMS) is the commonest type of soft-tissue sarcoma in children. Patients with metastatic RMS continue to have very poor prognosis. Recently, several works have demonstrated a connection between Notch pathway activation and the regulation of cell motility and invasiveness...

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Detalles Bibliográficos
Autores principales: Masià, A, Almazán-Moga, A, Velasco, P, Reventós, J, Torán, N, Sánchez de Toledo, J, Roma, J, Gallego, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494428/
https://www.ncbi.nlm.nih.gov/pubmed/22976797
http://dx.doi.org/10.1038/bjc.2012.411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494428/
https://www.ncbi.nlm.nih.gov/pubmed/22976797
http://dx.doi.org/10.1038/bjc.2012.411

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