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Human responses against HER-2-positive cancer cells in human immune system-engrafted mice

BACKGROUND: Human immune system (HIS)-engrafted mice are new tools to investigate human immune responses. Here, we used HIS mice to study human immune responses against human HER-2-positive cancer cells and their ability to control tumour growth and metastasis. METHODS: BALB/c Rag2(−/−), Il2rg(−/−)...

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Detalles Bibliográficos
Autores principales: De Giovanni, C, Nicoletti, G, Landuzzi, L, Romani, F, Croci, S, Palladini, A, Murgo, A, Antognoli, A, Ianzano, M L, Stivani, V, Grosso, V, Iezzi, M, Stramucci, L, Barbieri, E, Lemoli, R M, Nanni, P, Lollini, P-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494430/
https://www.ncbi.nlm.nih.gov/pubmed/22929887
http://dx.doi.org/10.1038/bjc.2012.394