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Human responses against HER-2-positive cancer cells in human immune system-engrafted mice
BACKGROUND: Human immune system (HIS)-engrafted mice are new tools to investigate human immune responses. Here, we used HIS mice to study human immune responses against human HER-2-positive cancer cells and their ability to control tumour growth and metastasis. METHODS: BALB/c Rag2(−/−), Il2rg(−/−)...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494430/ https://www.ncbi.nlm.nih.gov/pubmed/22929887 http://dx.doi.org/10.1038/bjc.2012.394 |