Cargando…
Human responses against HER-2-positive cancer cells in human immune system-engrafted mice
BACKGROUND: Human immune system (HIS)-engrafted mice are new tools to investigate human immune responses. Here, we used HIS mice to study human immune responses against human HER-2-positive cancer cells and their ability to control tumour growth and metastasis. METHODS: BALB/c Rag2(−/−), Il2rg(−/−)...
Autores principales: | De Giovanni, C, Nicoletti, G, Landuzzi, L, Romani, F, Croci, S, Palladini, A, Murgo, A, Antognoli, A, Ianzano, M L, Stivani, V, Grosso, V, Iezzi, M, Stramucci, L, Barbieri, E, Lemoli, R M, Nanni, P, Lollini, P-L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494430/ https://www.ncbi.nlm.nih.gov/pubmed/22929887 http://dx.doi.org/10.1038/bjc.2012.394 |
Ejemplares similares
-
Multiorgan Metastasis of Human HER-2(+) Breast Cancer in Rag2(−/−);Il2rg(−/−) Mice and Treatment with PI3K Inhibitor
por: Nanni, Patrizia, et al.
Publicado: (2012) -
Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis
por: De Giovanni, Carla, et al.
Publicado: (2019) -
Vaccines against human HER2 prevent mammary carcinoma in mice transgenic for human HER2
por: De Giovanni, Carla, et al.
Publicado: (2014) -
Interleukin-15 is required for immunosurveillance and immunoprevention of HER2/neu-driven mammary carcinogenesis
por: Croci, Stefania, et al.
Publicado: (2015) -
Preclinical Therapy of Disseminated HER-2(+) Ovarian and Breast Carcinomas with a HER-2-Retargeted Oncolytic Herpesvirus
por: Nanni, Patrizia, et al.
Publicado: (2013)