Endothelial cell metabolism and implications for cancer therapy

Tumour tissue is characterised by fluctuating oxygen concentrations, decreased nutrient supply, and acidic pH. The primarily glycolytic metabolism of tumour cells contributes to this, with increased glucose consumption and increased lactate secretion. Endothelial cells are particularly challenged wh...

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Detalles Bibliográficos
Autores principales: Harjes, U, Bensaad, K, Harris, A L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494441/
https://www.ncbi.nlm.nih.gov/pubmed/23047591
http://dx.doi.org/10.1038/bjc.2012.398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494441/
https://www.ncbi.nlm.nih.gov/pubmed/23047591
http://dx.doi.org/10.1038/bjc.2012.398

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