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Single low-dose cyclophosphamide combined with interleukin-12 gene therapy is superior to a metronomic schedule in inducing immunity against colorectal carcinoma in mice

The use of conventional cytotoxic agents at metronomic schedules, alone or in combination with targeted agents or immunotherapy, is being explored as a promising anticancer strategy. We previously reported a potent antitumor effect of a single low-dose cyclophosphamide and interleukin-12 (IL-12) gen...

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Detalles Bibliográficos
Autores principales: Malvicini, Mariana, Alaniz, Laura, Bayo, Juan, Garcia, Mariana, Piccioni, Flavia, Fiore, Esteban, Atorrasagasti, Catalina, Aquino, Jorge B., Matar, Pablo, Mazzolini, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494618/
https://www.ncbi.nlm.nih.gov/pubmed/23170252
http://dx.doi.org/10.4161/onci.20684