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Redirecting neutrophils against bladder cancer cells by BCG and Smac mimetic combination

Intravesical bacillus Calmette-Guérin (BCG) immunotherapy results in neutrophil recruitment and subsequent secretion of cytokines to eliminate non-muscle invasive bladder cancer cells. However, bladder cancer cells often resist BCG immunotherapy. Thus, understanding the mechanism of action of BCG, a...

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Detalles Bibliográficos
Autores principales: Jinesh G., Goodwin, Kamat, Ashish M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494630/
https://www.ncbi.nlm.nih.gov/pubmed/23170264
http://dx.doi.org/10.4161/onci.20928