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Rapamycin: A rheostat for CD8(+) T-cell-mediated tumor therapy

Vaccines that generate Ag-specific CD8(+) T-cell responses of appropriate quality, magnitude and duration are highly desirable. The ability of mTOR to regulate CD8(+) T-cell functional differentiation must be exploited for clinical benefit. In a recent paper, we report that varying the regimen of ra...

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Detalles Bibliográficos
Autores principales: Srivastava, Rupesh K., Utley, Adam, Shrikant, Protul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494641/
https://www.ncbi.nlm.nih.gov/pubmed/23170275
http://dx.doi.org/10.4161/onci.20663