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Targeting the right regulatory T-cell population for tumor immunotherapy

Regulatory T cells (Tregs) that suppress tumor-specific T cell-mediated immune responses are the subject of an intense wave of investigation. We recently reported that a subset of Tregs, namely effector/memory CD25(low) cells, are responsible for suppressing high avidity tumor-specific T cells in mo...

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Detalles Bibliográficos
Autores principales: Weiss, Vivian L., Lee, Timothy H., Jaffee, Elizabeth M., Armstrong, Todd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494642/
https://www.ncbi.nlm.nih.gov/pubmed/23170276
http://dx.doi.org/10.4161/onci.20664