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Adult Pancreas Side Population Cells Expand after β Cell Injury and Are a Source of Insulin-Secreting Cells

Pancreas stem cells are a potential source of insulin-producing β cells for the therapy of diabetes. In adult tissues the ‘side population’ (SP) of cells that effluxes the DNA binding dye Hoechst 33342 through ATP-binding cassette transporters has stem cell properties. We hypothesised therefore that...

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Detalles Bibliográficos
Autores principales: Banakh, Ilia, Gonez, Leonel J., Sutherland, Robyn M., Naselli, Gaetano, Harrison, Leonard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494669/
https://www.ncbi.nlm.nih.gov/pubmed/23152835
http://dx.doi.org/10.1371/journal.pone.0048977