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Remarkable Diversity in the Enzymes Catalyzing the Last Step in Synthesis of the Pimelate Moiety of Biotin

Biotin synthesis in Escherichia coli requires the functions of the bioH and bioC genes to synthesize the precursor pimelate moiety by use of a modified fatty acid biosynthesis pathway. However, it was previously noted that bioH has been replaced with bioG or bioK within the biotin synthetic gene clu...

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Detalles Bibliográficos
Autores principales: Shapiro, Madelyn M., Chakravartty, Vandana, Cronan, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494674/
https://www.ncbi.nlm.nih.gov/pubmed/23152908
http://dx.doi.org/10.1371/journal.pone.0049440