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Structure-Function Analysis of the Glioma Targeting NFL-TBS.40-63 Peptide Corresponding to the Tubulin-Binding Site on the Light Neurofilament Subunit

We previously reported that a 24 amino acid peptide (NFL-TBS.40-63) corresponding to the tubulin-binding site located on the light neurofilament subunit, selectively enters in glioblastoma cells where it disrupts their microtubule network and inhibits their proliferation. Here, we analyzed the struc...

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Detalles Bibliográficos
Autores principales: Berges, Raphael, Balzeau, Julien, Takahashi, Masayuki, Prevost, Chantal, Eyer, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494675/
https://www.ncbi.nlm.nih.gov/pubmed/23152907
http://dx.doi.org/10.1371/journal.pone.0049436