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The ABCA1 Gene R230C Variant Is Associated with Decreased Risk of Premature Coronary Artery Disease: The Genetics of Atherosclerotic Disease (GEA) Study

BACKGROUND: ABCA1 genetic variation is known to play a role in HDL-C levels and various studies have also implicated ABCA1 variation in cardiovascular risk. The functional ABCA1/R230C variant is frequent in the Mexican population and has been consistently associated with low HDL-C concentrations. Al...

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Detalles Bibliográficos
Autores principales: Villarreal-Molina, Teresa, Posadas-Romero, Carlos, Romero-Hidalgo, Sandra, Antúnez-Argüelles, Erika, Bautista-Grande, Araceli, Vargas-Alarcón, Gilberto, Kimura-Hayama, Eric, Canizales-Quinteros, Samuel, Juárez-Rojas, Juan Gabriel, Posadas-Sánchez, Rosalinda, Cardoso-Saldaña, Guillermo, Medina-Urrutia, Aída, González-Salazar, María del Carmen, Martínez-Alvarado, Rocío, Jorge-Galarza, Esteban, Carnevale, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494680/
https://www.ncbi.nlm.nih.gov/pubmed/23152888
http://dx.doi.org/10.1371/journal.pone.0049285