Targeting the Acute Promyelocytic Leukemia-Associated Fusion Proteins PML/RARα and PLZF/RARα with Interfering Peptides

In acute promyelocytic leukemia (APL), hematopoietic differentiation is blocked and immature blasts accumulate in the bone marrow and blood. APL is associated with chromosomal aberrations, including t(15;17) and t(11;17). For these two translocations, the retinoic acid receptor alpha (RARα) is fused...

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Detalles Bibliográficos
Autores principales: Beez, Sabine, Demmer, Philipp, Puccetti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494703/
https://www.ncbi.nlm.nih.gov/pubmed/23152790
http://dx.doi.org/10.1371/journal.pone.0048636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494703/
https://www.ncbi.nlm.nih.gov/pubmed/23152790
http://dx.doi.org/10.1371/journal.pone.0048636

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