Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis

A significant proportion of enzymes display cooperativity in binding ligand molecules, and such effects have an important impact on metabolic regulation. This is easiest to understand in the case of positive cooperativity. Sharp responses to changes in metabolite concentrations can allow organisms t...

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Detalles Bibliográficos
Autores principales: Bush, Eliot C., Clark, Anne E., DeBoever, Chris M., Haynes, Lillian E., Hussain, Sidra, Ma, Singer, McDermott, Matthew M., Novak, Adam M., Wentworth, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494708/
https://www.ncbi.nlm.nih.gov/pubmed/23152821
http://dx.doi.org/10.1371/journal.pone.0048920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494708/
https://www.ncbi.nlm.nih.gov/pubmed/23152821
http://dx.doi.org/10.1371/journal.pone.0048920

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