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Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver

Fatty liver (hepatic steatosis) is associated with nucleotide turnover, loss of ATP and generation of adenosine monophosphate (AMP). It is well known that in fatty liver, activity of the AMP-activated kinase (AMPK) is reduced and that its stimulation can prevent hepatic steatosis by both enhancing f...

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Detalles Bibliográficos
Autores principales: Lanaspa, Miguel A., Cicerchi, Christina, Garcia, Gabriela, Li, Nanxing, Roncal-Jimenez, Carlos A., Rivard, Christopher J., Hunter, Brandi, Andrés-Hernando, Ana, Ishimoto, Takuji, Sánchez-Lozada, Laura G., Thomas, Jeffrey, Hodges, Robert S., Mant, Colin T., Johnson, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494720/
https://www.ncbi.nlm.nih.gov/pubmed/23152807
http://dx.doi.org/10.1371/journal.pone.0048801