Cargando…
Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver
Fatty liver (hepatic steatosis) is associated with nucleotide turnover, loss of ATP and generation of adenosine monophosphate (AMP). It is well known that in fatty liver, activity of the AMP-activated kinase (AMPK) is reduced and that its stimulation can prevent hepatic steatosis by both enhancing f...
Autores principales: | Lanaspa, Miguel A., Cicerchi, Christina, Garcia, Gabriela, Li, Nanxing, Roncal-Jimenez, Carlos A., Rivard, Christopher J., Hunter, Brandi, Andrés-Hernando, Ana, Ishimoto, Takuji, Sánchez-Lozada, Laura G., Thomas, Jeffrey, Hodges, Robert S., Mant, Colin T., Johnson, Richard J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494720/ https://www.ncbi.nlm.nih.gov/pubmed/23152807 http://dx.doi.org/10.1371/journal.pone.0048801 |
Ejemplares similares
-
Opposing Activity Changes in AMP Deaminase and AMP-Activated Protein Kinase in the Hibernating Ground Squirrel
por: Lanaspa, Miguel A., et al.
Publicado: (2015) -
Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver
por: Lanaspa, Miguel A., et al.
Publicado: (2012) -
Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor
por: Andres-Hernando, Ana, et al.
Publicado: (2021) -
Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
por: Andres-Hernando, Ana, et al.
Publicado: (2017) -
AMP Deaminase 3 Deficiency Enhanced 5′-AMP Induction of Hypometabolism
por: Daniels, Isadora Susan, et al.
Publicado: (2013)