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Systematic Identification of Synergistic Drug Pairs Targeting HIV

The systematic identification of effective drug combinations has been hindered by the unavailability of methods that can explore the large combinatorial search space of drug interactions. Here we present a multiplex screening method named MuSIC (Multiplex Screening for Interacting Compounds), which...

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Detalles Bibliográficos
Autores principales: Tan, Xu, Hu, Long, Luquette, Lovelace J., Gao, Geng, Liu, Yifang, Qu, Hongjing, Xi, Ruibin, Lu, Zhi John, Park, Peter J., Elledge, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494743/
https://www.ncbi.nlm.nih.gov/pubmed/23064238
http://dx.doi.org/10.1038/nbt.2391