Aurora Kinase A deficiency during skin development impairs cell division and stratification

Aurora Kinase-A (Aurora-A) promotes timely entry into mitosis, centrosome maturation, and formation of bipolar spindles. To address the role of Aurora-A in skin development and homeostasis, we interbred a floxed Aurora-A (Aurora-A(fl)) mouse with the Cre-deleter strain, K14.Cre. Aurora-A(fl/fl);Krt1...

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Detalles Bibliográficos
Autores principales: Torchia, Enrique C., Zhang, Lei, Huebner, Aaron J., Sen, Subrata, Roop, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494779/
https://www.ncbi.nlm.nih.gov/pubmed/22832491
http://dx.doi.org/10.1038/jid.2012.249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494779/
https://www.ncbi.nlm.nih.gov/pubmed/22832491
http://dx.doi.org/10.1038/jid.2012.249

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