A complex of α(6) integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

Homing of colorectal cancer (CRC) cells to the liver is a non-random process driven by a crosstalk between tumour cells and components of the host tissue. Here we report the isolation of a liver metastasis-specific peptide ligand (CGIYRLRSC) that binds a complex of E-cadherin and α(6) integrin on th...

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Detalles Bibliográficos
Autores principales: Marchiò, Serena, Soster, Marco, Cardaci, Sabrina, Muratore, Andrea, Bartolini, Alice, Barone, Vanessa, Ribero, Dario, Monti, Maria, Bovino, Paola, Sun, Jessica, Giavazzi, Raffaella, Asioli, Sofia, Cassoni, Paola, Capussotti, Lorenzo, Pucci, Piero, Bugatti, Antonella, Rusnati, Marco, Pasqualini, Renata, Arap, Wadih, Bussolino, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494873/
https://www.ncbi.nlm.nih.gov/pubmed/23070965
http://dx.doi.org/10.1002/emmm.201101164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494873/
https://www.ncbi.nlm.nih.gov/pubmed/23070965
http://dx.doi.org/10.1002/emmm.201101164

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