Cargando…

A complex of α(6) integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

Homing of colorectal cancer (CRC) cells to the liver is a non-random process driven by a crosstalk between tumour cells and components of the host tissue. Here we report the isolation of a liver metastasis-specific peptide ligand (CGIYRLRSC) that binds a complex of E-cadherin and α(6) integrin on th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marchiò, Serena, Soster, Marco, Cardaci, Sabrina, Muratore, Andrea, Bartolini, Alice, Barone, Vanessa, Ribero, Dario, Monti, Maria, Bovino, Paola, Sun, Jessica, Giavazzi, Raffaella, Asioli, Sofia, Cassoni, Paola, Capussotti, Lorenzo, Pucci, Piero, Bugatti, Antonella, Rusnati, Marco, Pasqualini, Renata, Arap, Wadih, Bussolino, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494873/ https://www.ncbi.nlm.nih.gov/pubmed/23070965 http://dx.doi.org/10.1002/emmm.201101164

Ejemplares similares

Brain endothelial cell‐targeted gene therapy of neurovascular disorders
por: Marchiò, Serena, et al.
Publicado: (2016)

Heparin/Heparan Sulfate Proteoglycans Glycomic Interactome in Angiogenesis: Biological Implications and Therapeutical Use
por: Chiodelli, Paola, et al.
Publicado: (2015)

Vascular Targeting: Recent Advances and Therapeutic Perspectives
por: Hajitou, Amin, et al.
Publicado: (2006)

Aminopeptidase N inhibitors and SARS
por: Kontoyiannis, Dimitrios P, et al.
Publicado: (2003)

Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models
por: Peraldo-Neia, Caterina, et al.
Publicado: (2014)

Targeted dual-color silica nanoparticles provide univocal identification of micrometastases in preclinical models of colorectal cancer
por: Soster, Marco, et al.
Publicado: (2012)

Bone marrow-derived CD13(+) cells sustain tumor progression: A potential non-malignant target for anticancer therapy
por: Dondossola, Eleonora, et al.
Publicado: (2014)

Ligand-directed Cancer Gene Therapy to Angiogenic Vasculature
por: Driessen, Wouter H.P., et al.
Publicado: (2009)

Display technologies: Application for the discovery of drug and gene delivery agents()
por: Sergeeva, Anna, et al.
Publicado: (2006)

Leveraging the scientific findings to develop therapeutic strategies for dormant breast cancer cells
por: Ferrer, Alejandra, et al.
Publicado: (2022)

Does the RAAS play a role in loss of taste and smell during COVID-19 infections?
por: Luchiari, Heloise R., et al.
Publicado: (2020)

Repurposing Ferumoxytol as a Breast Cancer-Associated Macrophage Tracer with Five-Dimensional Quantitative [Fe]MRI of SPION Dynamics
por: Sillerud, Laurel O., et al.
Publicado: (2021)

Polyanionic Drugs and Viral Oncogenesis: a Novel Approach to Control Infection, Tumor-associated Inflammation and Angiogenesis
por: Urbinati, Chiara, et al.
Publicado: (2008)

Angiopoietin-like protein 2 and angiopoietin-like protein 6 levels in patients with nonalcoholic fatty liver disease
por: Erkan, Gulbanu, et al.
Publicado: (2016)

Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity
por: Rusnati, Marco, et al.
Publicado: (2009)

Preclinical optimization of a diode laser-based clamp-free partial nephrectomy in a large animal model
por: Andrade, Weslley S., et al.
Publicado: (2023)

Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction
por: Li, Jianxue, et al.
Publicado: (2020)

Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes
por: Qaddoumi, Mohammad G., et al.
Publicado: (2020)

Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces
por: Lubin, Joseph H., et al.
Publicado: (2021)

Distinctive pathological and clinical features of lung carcinoids with high proliferation index
por: Marchiò, Caterina, et al.
Publicado: (2017)

Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications
por: Bugatti, Antonella, et al.
Publicado: (2019)

Identification of Novel Immunoregulatory Molecules in Human Thymic Regulatory CD4(+)CD25(+) T Cells by Phage Display
por: Porto, Georgia, et al.
Publicado: (2011)

OR14-6 The Role of the Angiopoietin-Tie2 Pathway in Microvascular Complications of Diabetes Mellitus
por: Brigell, Mitchell, et al.
Publicado: (2019)

Anti-angiogenic Targets: Angiopoietin and Angiopoietin Receptors
por: Kiss, Elina A., et al.
Publicado: (2019)

An Antimicrobial Peptidomimetic Induces Mucorales Cell Death through Mitochondria-Mediated Apoptosis
por: Barbu, E. Magda, et al.
Publicado: (2013)

An Anti-Ubiquitin Antibody Response in Transitional Cell Carcinoma of the Urinary Bladder
por: Ardelt, Peter U., et al.
Publicado: (2015)

Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking
por: Daquinag, Alexes C., et al.
Publicado: (2021)

Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses
por: Teixeira, Andre A, et al.
Publicado: (2017)

Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting
por: Staquicini, Daniela I., et al.
Publicado: (2017)

Association of serum angiopoietin-1, angiopoietin-2 and angiopoietin-2 to angiopoietin-1 ratio with heart failure in patients with acute myocardial infarction
por: CHEN, SHAOMIN, et al.
Publicado: (2013)

Direct and Allosteric Inhibition of the FGF2/HSPGs/FGFR1 Ternary Complex Formation by an Antiangiogenic, Thrombospondin-1-Mimic Small Molecule
por: Pagano, Katiuscia, et al.
Publicado: (2012)

Bottom-Up Assembly of Hydrogels from Bacteriophage and Au Nanoparticles: The Effect of Cis- and Trans-Acting Factors
por: Souza, Glauco R., et al.
Publicado: (2008)

Peptidase Substrates via Global Peptide Profiling
por: Tagore, Debarati M., et al.
Publicado: (2008)

Increased Serum Angiopoietin-Like 6 Ahead of Metabolic Syndrome in a Prospective Cohort Study
por: Namkung, Jun, et al.
Publicado: (2019)

Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells
por: Gualandris, Anna, et al.
Publicado: (2021)

Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na(+),K(+)-ATPase Blocks HIV-1 Infection
por: Agostini, Silvia, et al.
Publicado: (2017)

α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
por: Bugatti, Kelly
Publicado: (2021)

Next-Generation Phage Display: Integrating and Comparing Available Molecular Tools to Enable Cost-Effective High-Throughput Analysis
por: Dias-Neto, Emmanuel, et al.
Publicado: (2009)

Do Pandemics Obey the Elliott Wave Principle of Financial Markets?
por: Dogra, Prashant, et al.
Publicado: (2021)

Is the worst of the COVID-19 global pandemic yet to come? Application of financial mathematics as candidate predictive tools
por: Dogra, Prashant, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qesvie2uv820ku4nlvnjp1566u