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Influence of Statins locally applied from orthopedic implants on osseous integration

BACKGROUND: Simvastatin increases the expression of bone morphogenetic protein 2 (BMP-2) in osteoblasts, therefore it is important to investigate the influence of statins on bone formation, fracture healing and implant integration. The aim of the present study was to investigate the effect of Simvas...

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Detalles Bibliográficos
Autores principales: Pauly, Stephan, Back, David A, Kaeppler, Kathrin, Haas, Norbert P, Schmidmaier, Gerhard, Wildemann, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495199/
https://www.ncbi.nlm.nih.gov/pubmed/23102098
http://dx.doi.org/10.1186/1471-2474-13-208