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Technical Considerations for Reduced Representation Bisulfite Sequencing with Multiplexed Libraries
Reduced representation bisulfite sequencing (RRBS), which couples bisulfite conversion and next generation sequencing, is an innovative method that specifically enriches genomic regions with a high density of potential methylation sites and enables investigation of DNA methylation at single-nucleoti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495292/ https://www.ncbi.nlm.nih.gov/pubmed/23193365 http://dx.doi.org/10.1155/2012/741542 |