Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs

BACKGROUND: The majority of published gene-expression studies have used RNA isolated from whole cells, overlooking the potential impact of including nuclear transcriptome in the analyses. In this study, mRNA fractions from the cytoplasm and from whole cells (total RNA) were prepared from three human...

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Detalles Bibliográficos
Autores principales: Solnestam, Beata Werne, Stranneheim, Henrik, Hällman, Jimmie, Käller, Max, Lundberg, Emma, Lundeberg, Joakim, Akan, Pelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495644/
https://www.ncbi.nlm.nih.gov/pubmed/23110385
http://dx.doi.org/10.1186/1471-2164-13-574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495644/
https://www.ncbi.nlm.nih.gov/pubmed/23110385
http://dx.doi.org/10.1186/1471-2164-13-574

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