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Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs
BACKGROUND: The majority of published gene-expression studies have used RNA isolated from whole cells, overlooking the potential impact of including nuclear transcriptome in the analyses. In this study, mRNA fractions from the cytoplasm and from whole cells (total RNA) were prepared from three human...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495644/ https://www.ncbi.nlm.nih.gov/pubmed/23110385 http://dx.doi.org/10.1186/1471-2164-13-574 |