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Computational codon optimization of synthetic gene for protein expression
BACKGROUND: The construction of customized nucleic acid sequences allows us to have greater flexibility in gene design for recombinant protein expression. Among the various parameters considered for such DNA sequence design, individual codon usage (ICU) has been implicated as one of the most crucial...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495653/ https://www.ncbi.nlm.nih.gov/pubmed/23083100 http://dx.doi.org/10.1186/1752-0509-6-134 |