Sickle cell mice exhibit mechanical allodynia and enhanced responsiveness in light touch cutaneous mechanoreceptors

BACKGROUND: Sickle cell disease (SCD) is associated with both acute vaso-occlusive painful events as well as chronic pain syndromes, including heightened sensitivity to touch. We have previously shown that mice with severe SCD (HbSS mice; express 100% human sickle hemoglobin in red blood cells; RBCs...

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Detalles Bibliográficos
Autores principales: Garrison, Sheldon R, Kramer, Audra A, Gerges, Nashaat Z, Hillery, Cheryl A, Stucky, Cheryl L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495672/
https://www.ncbi.nlm.nih.gov/pubmed/22963123
http://dx.doi.org/10.1186/1744-8069-8-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495672/
https://www.ncbi.nlm.nih.gov/pubmed/22963123
http://dx.doi.org/10.1186/1744-8069-8-62

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