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CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer

Much effort in cancer research has focused on the tiny part of our genome that codes for mRNA. However, it has recently been recognized that microRNAs also contribute decisively to tumorigenesis. Studies have also shown that epigenetic silencing by CpG island hypermethylation of microRNAs with tumor...

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Detalles Bibliográficos
Autores principales: Ferreira, Humberto J., Heyn, Holger, Moutinho, Cátia, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495749/
https://www.ncbi.nlm.nih.gov/pubmed/22617881
http://dx.doi.org/10.4161/rna.19353