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CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer
Much effort in cancer research has focused on the tiny part of our genome that codes for mRNA. However, it has recently been recognized that microRNAs also contribute decisively to tumorigenesis. Studies have also shown that epigenetic silencing by CpG island hypermethylation of microRNAs with tumor...
Autores principales: | Ferreira, Humberto J., Heyn, Holger, Moutinho, Cátia, Esteller, Manel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495749/ https://www.ncbi.nlm.nih.gov/pubmed/22617881 http://dx.doi.org/10.4161/rna.19353 |
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