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Development of new plasmid DNA vaccine vectors with R1-based replicons
BACKGROUND: There has been renewed interest in biopharmaceuticals based on plasmid DNA (pDNA) in recent years due to the approval of several veterinary DNA vaccines, on-going clinical trials of human pDNA-based therapies, and significant advances in adjuvants and delivery vehicles that have helped o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495755/ https://www.ncbi.nlm.nih.gov/pubmed/22889338 http://dx.doi.org/10.1186/1475-2859-11-107 |