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Development of new plasmid DNA vaccine vectors with R1-based replicons

BACKGROUND: There has been renewed interest in biopharmaceuticals based on plasmid DNA (pDNA) in recent years due to the approval of several veterinary DNA vaccines, on-going clinical trials of human pDNA-based therapies, and significant advances in adjuvants and delivery vehicles that have helped o...

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Detalles Bibliográficos
Autores principales: Bower, Diana M, Prather, Kristala LJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495755/
https://www.ncbi.nlm.nih.gov/pubmed/22889338
http://dx.doi.org/10.1186/1475-2859-11-107